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Lower urinary tract obstruction (LUTO), also known as bladder outlet obstruction (BOO), is a rare condition which occurs more commonly in males than females. LUTO is a blockage either at the base of the bladder or at the urethra, which is the tube that drains urine from the bladder. Depending on the severity of the blockage, the drainage of.


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Lower Urinary Tract Obstruction. View in PDF Format. Fetal lower urinary tract obstruction (LUTO) is a rare condition that is caused by a blockage of fetal urination. Because the baby cannot empty the bladder, the baby's bladder subsequently becomes very large and inflated. Also, because the amniotic fluid is essentially composed of the baby.


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Lower urinary tract obstructions (LUTO), also known as obstructive uropathy, are rare birth defects that occur in 1 in 5,000 to 7,000 births, commonly in male fetuses. The underlying cause is a partial or complete obstruction of the urethra, the tube that connects the bladder to the amniotic fluid space around the fetus.


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babies with LUTO die, even if fetal therapy was performed. How sick a baby will be after birth depends on how severe the lung and kidney damage are, and depends on the cause of the baby's LUTO. For these reasons, it is important to have a thorough evaluation of a baby with LUTO in the NICU, and close monitoring by the baby's pediatrician.


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Fetal lower urinary tract obstruction (LUTO) is a serious condition, which commonly results in marked perinatal morbidity and mortality. The characteristic prenatal presentation of LUTO includes an enlarged bladder with bilateral obstructive uropathy. While mild forms of the disease result in minimal clinical sequelae, the more severe forms commonly lead to oligohydramnios, dysplastic changes.


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A final diagnosis was achieved in 143 cases, including 124 of LUTO and 19 reclassified after birth as non‐obstructive megacystis. The optimal bladder volume cut‐off for prediction of LUTO was 35 cm 3 (area under the curve (AUC) = 0.7, P = 0.03). The clinical score formulated on the basis of the multivariate analysis included fetal sex.


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Lower urinary tract obstruction (LUTO) is a complex fetal genitourinary disorder associated with significant morbidity and mortality, which requires diagnostic and management advancement to improve fetal outcomes. While LUTO is estimated to occur in only 2.2-3.3 cases per 10,000 [ 1, 2 ], it can have a devastating impact on the fetus and on.


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Bladder outlet obstruction, a type of lower urinary tract obstruction (LUTO), is a rare birth defect occurring in about 2.2 out of 10,000 births. It occurs most often in males due to blockage of the flow of urine from the urethra, which is the tube that drains urine from the bladder out of the body.


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INTRODUCTION. The term 'lower urinary tract obstruction' (LUTO) describes a heterogeneous group of conditions in which the normal urethral egress of urine from the fetal bladder is impaired 1.LUTO occurs in approximately three out of 10 000 pregnancies 2 and is associated with high mortality and morbidity due to pulmonary hypoplasia and progressive renal dysfunction, with the former being.


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Overall, 5 of 9 LUTO fetuses (55%) undergoing VAS with the Somatex ® intrauterine shunt system showed long-term survival beyond the neonatal period of 28 d (5/9; 55%) with varying morbidity. Fetal therapy of LUTO (lower urinary tract obstruction) - a follow-up observational study J Matern.


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Fetal lower urinary tract obstruction (LUTO) is a condition that occurs when the baby's urethra, the tube that transports urine from the bladder to the outside of the body during urination (Figure 1), becomes partially or completely blocked. The condition is serious for several reasons.


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Introduction Fetal lower urinary tract obstruction (LUTO) affects ~2-3 out of 10,000 fetuses with a wide spectrum of severity 1. LUTO diagnosis can be either prenatal or postnatal, with a 1:1.


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The algorithm includes the following steps: treatment of fetuses with isolated severe LUTO within days from the first diagnosis (from as early as 12 weeks of gestation onward); karyotyping.


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Abstract. Fetal lower urinary tract obstruction (LUTO) is a serious condition, which commonly results in marked perinatal morbidity and mortality. The characteristic prenatal presentation of LUTO includes an enlarged bladder with bilateral obstructive uropathy. While mild forms of the disease result in minimal clinical sequelae, the more severe.