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Vitamin B 12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. It is one of eight B vitamins.It is required by animals, which use it as a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. It is important in the normal functioning of the nervous system via its role in the synthesis of myelin, and in the circulatory system in the maturation.

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People with vitamin B12 deficiency can have neurological symptoms and/or damage without anemia (lack of red blood cells). General physical symptoms of vitamin B12 deficiency can include: Feeling very tired or weak. Experiencing nausea, vomiting or diarrhea. Not feeling as hungry as usual. Weight loss.

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1,000 to 2,000 times as much vitamin B12 as you'd typically eat in a day, so the of vitamin B12 deficiency can take several years to appear. If you have a vitamin B12 deficiency, you may feel tired or weak. These are symptoms of megaloblastic anemia, which is a hallmark of vitamin B12 deficiency. You might also have pale skin, heart.

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Vitamin B12 helps your body produce energy by converting carbohydrates into glucose. Vitamin B12 also helps the nervous system function effectively. Working together with vitamin B9 (folate), it helps iron function better and helps the body to make healthy red blood cells. Together, folate and vitamin B12 work to produce S-adenosylmethionine.

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Vitamin C and E supplements won't ward off diabetes and diabetes complications. Until the research shows a clear benefit, it's best to pass on these. The jury's still out on vitamin D. There is an association between higher concentrations of vitamin D in the blood during childhood and a lower risk of type 1 diabetes.

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Vitamin B-12 (cobalamin) plays an essential role in red blood cell formation, cell metabolism, nerve function and the production of DNA, the molecules inside cells that carry genetic information. Food sources of vitamin B-12 include poultry, meat, fish and dairy products. Vitamin B-12 is also added to some foods, such as fortified breakfast.

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Overview. Vitamin B12 is an essential vitamin found in foods such as meat, fish, and dairy. It can also be made in a lab and is often taken with other B vitamins. Vitamin B12 is required for the.

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Vitamin B12 is an essential micronutrient required for optimal hemopoetic, neuro-cognitive and cardiovascular function. Biochemical and clinical vitamin B12 deficiency has been demonstrated to be highly prevalent among patients with type 1 and type 2 diabetes mellitus.

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Vitamin B12 - Health Professional Fact Sheet. 35 ]. Approximately 24% of men and 29% of women reported using a dietary supplement containing vitamin B12 in NHANES 2017-2018 [ ]. The proportion in children ranged from 30% of those age 2-5 years to 10% of adolescents age 12-19. Mean vitamin B12 intakes among supplement users from both foods.

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BackgroundMetformin is the most common oral hypoglycemic used and associated with certain abnormalities. The objective was to evaluate and define the occurrence and bases of vitamin B12 deficiency amongst patients on Metformin for diabetes mellitus type.

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B-12 deficiency can also lead to peripheral neuropathy with symptoms that may include numbness, weakness, pain, and paresthesia (a burning or itchy sensation of the skin). It's usually felt on.